MEK/ERK signaling is involved in the role of VEGF and IGF1 in cardiomyocyte differentiation of mouse adipose tissue-derived stromal cells

Article ID	Journal	Published Year	Pages	File Type
5605607	International Journal of Cardiology	2017	34 Pages	PDF

Abstract

These findings indicated that VEGF and IGF1 were critical factors for the spontaneous cardiac differentiation of BATDCs, and MEK/ERK signaling was involved in the role of VEGF and IGF1. VEGF and IGF1 could be used to promote the development of cardiomyocyte phenotype in WATDCs.

Keywords

cTNT GATA4 GATA binding protein 4 Insulin-like growth factor 1 (IGF1)Igf1 cardiac troponin T Cardiomyocyte differentiation Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Vascular endothelial growth factor (VEGF)insulin-like growth factor 1