| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5605625 | International Journal of Cardiology | 2017 | 5 Pages |
Abstract
In the present study, acute infusion of levosimendan resulted in an abbreviation of ventricular repolarization and a reduction of ERP. This led to a significantly elevated inducibility of ventricular fibrillation. In 8 of 10 hearts, incessant ventricular fibrillation occurred. These results suggest a proarrhythmic effect of levosimendan and might explain an increased mortality that coincided levosimendan treatment in a few small clinical studies.
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Authors
Gerrit Frommeyer, Anja Kohnke, Christian Ellermann, Dirk G. Dechering, Simon Kochhäuser, Christian Pott, Michael Fehr, Lars Eckardt,