Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5610693 | Journal of the American Society of Echocardiography | 2011 | 13 Pages |
Abstract
Clonal VL gene usage influences global cardiac function in AL, with patients having VlVI and VlII-III-associated amyloid more severely affected than those having Vk or VlI amyloid. Pulsed wave tissue Doppler imaging along with immunoglobulin gene analysis offers novel insights into prediction of mortality and cardiac dysfunction in AL after auto-SCT.
Keywords
DMIsystolic strainSSRcTNTBNPFLCAL amyloidosisimmunoglobulin Left ventricularcardiac biomarkerscardiac troponin TDoppler myocardial imagingFree light chainLV functionconfidence intervalSystolic strain ratehazard ratiobrain natriuretic peptideAutologous peripheral blood stem cell transplantationImmunoglobulin genes
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Diego MD, PhD, MS, Roshini S. PhD, Patricia A. MD, Angela MD, John C. MD, Ghormallah B. MBBS, Tammy D. RDCS, BA, Michelle K. MS, Morie A. MD, Fletcher A. MD, Theodore P. MD,