Do Additional Echocardiographic Variables Increase the Accuracy of E/e′ for Predicting Left Ventricular Filling Pressure in Normal Ejection Fraction? An Echocardiographic and Invasive Hemodynamic Study

In patients with preserved LVEFs, adding LAVi > 31 mL/m2 to E/e′ (when E/e′ was in the gray zone, but not when E/e′ was >13) significantly increased the accuracy of E/e′ alone for the estimation of LV filling pressure. These data support the notion of using several, rather than any single, Doppler echocardiographic parameter for the accurate assessment of LV diastolic function.