Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5615123 | Journal of Clinical Lipidology | 2017 | 7 Pages |
Abstract
- Low-density lipoproteins provide cholesterol to peripheral cells, including cancer cells.
- Cancer cells have higher cholesterol requirements to sustain tumor growth.
- Low-density lipoproteins <25Â mg/dL have been reported with PCSK9 inhibitors on top of a statin.
- A combination of cholesterol-lowering drugs could find use in cancer therapy.
- Clinical validation that cholesterol-lowering drugs slow cancer progression and metastasis is required.
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Authors
Anne MD, PhD, Frédéric PhD, Nabil G. PhD,