Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5615336 | Journal of Clinical Lipidology | 2017 | 21 Pages |
Abstract
This study characterizes for the first time in Argentina genetic variants associated with FH and suggest that the allelic heterogeneity of the FH in the country could have 1 relative common low-density lipoprotein receptor mutation. This knowledge is important for the genotype-phenotype correlation and for optimizing both cholesterol-lowering therapies and mutational analysis protocols. In addition, these data contribute to the understanding of the molecular basis of FH in Argentina.
Keywords
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Authors
Virginia G. PhD, Pablo MD, Ana Margarida PhD, MarÃa Beatriz MD, Alfredo MD, Juan PhD, Roxana PhD, Graciela MSci, Mafalda PhD, Laura E. PhD,