Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5615691 | The Journal of Heart and Lung Transplantation | 2017 | 11 Pages |
Abstract
Donor lungs develop a detectable and discriminatory pro-inflammatory signature in perfusate during EVLP. Blocking the IL-1β pathway during EVLP may reduce endothelial activation and subsequent neutrophil adhesion on reperfusion; this requires further investigation in vivo.
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Authors
Anders S.I. MD, Lee A. PhD, Colin PhD, Kasim BSc, Jonathan BSc, Paul BSc, Jonny MBBS, Rosalba MD, Marius MD, Simi PhD, James E. PhD, Nandor PhD, FRCA, John H. FRCS, Andrew J. PhD, FRCP,