Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5616001 | The Journal of Heart and Lung Transplantation | 2017 | 26 Pages |
Abstract
The presence of a BMPR2 mutation, per se, is not associated with an abnormal pulmonary vascular and right ventricular functional response to exercise in asymptomatic individuals. Longer follow-up will be required to determine whether a P/Q slope of >3 mm Hg/liter/min during exercise in normoxia or hypoxia is a sign of pre-clinical disease expression.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Guido MD, PhD, Andre MD, PhD, Thibault MD, Hilde BSc, Jan MD, PhD, Mathias MD, Steven MD, PhD, Piet MSc, PhD, Marion MD, PhD, Hein MD, PhD,