Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5618646 | Molecular Metabolism | 2017 | 9 Pages |
Abstract
A point mutation in Ffar1 abrogates the stimulatory effect of palmitate on GIIS, an effect that does not necessarily translate to HFD-induced glucose intolerance.
Keywords
HEPESGTTGLUT-2HFDSLC2A2Pax6GLP-1FFAR1N-ethyl-N-nitrosoureaENUIPITT4-(2-hydroxyethyl)-1-piperazine-ethanesulfonic acidintraperitoneal insulin tolerance testFree fatty acidsInsulin secretionGlucose-induced insulin secretionglucose tolerance testHigh fat dietglucagon like peptide-1glucose transporter 2Free fatty acid receptor 1
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Authors
Sibylle Sabrautzki, Gabriele Kaiser, Gerhard K.H. Przemeck, Felicia Gerst, Estela Lorza-Gil, Madhura Panse, Tina Sartorius, Miriam Hoene, Susan Marschall, Hans-Ulrich Häring, Martin HrabÄ de Angelis, Susanne Ullrich,