Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5618711 | Molecular Metabolism | 2017 | 13 Pages |
Abstract
PPG neurons respond directly to 5-HT with a 5-HT2C receptor-dependent increase in dendritic [Ca2+]i. Electrical responses to 5-HT revealed additional inhibitory effects due to somatic 5-HT1A receptors. Reciprocal innervation between 5-HT and PPG neurons suggests that the coordinated activity of these brainstem neurons may play a role in the regulation of food intake.
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Authors
Marie K. Holt, Ida J. Llewellyn-Smith, Frank Reimann, Fiona M. Gribble, Stefan Trapp,