Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5618747 | Molecular Metabolism | 2017 | 11 Pages |
Abstract
Our data show that the maturation of pancreatic β-cells requires the cooperative function of Foxa2 and Pdx1. Understanding the postnatal gene regulatory network of β-cell maturation will help to decipher pathomechanisms of diabetes and identify triggers to regenerate dedifferentiated β-cell mass.
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Authors
Aimée Bastidas-Ponce, Sara S. Roscioni, Ingo Burtscher, Erik Bader, Michael Sterr, Mostafa Bakhti, Heiko Lickert,