| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5618812 | Molecular Metabolism | 2016 | 11 Pages |
Abstract
Our data indicate that impaired muscle BCAA catabolism may contribute to the development of insulin resistance by perturbing both amino acid and fatty acid metabolism and suggest that targeting BCAA metabolism may hold promise for prevention or treatment of T2D.
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Authors
Carles Lerin, Allison B. Goldfine, Tanner Boes, Manway Liu, Simon Kasif, Jonathan M. Dreyfuss, Ana Luisa De Sousa-Coelho, Grace Daher, Irini Manoli, Justin R. Sysol, Elvira Isganaitis, Niels Jessen, Laurie J. Goodyear, Kirk Beebe, Walt Gall,