Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5621945 | Thrombosis Research | 2017 | 6 Pages |
Abstract
FXIII deficiency impairs fibrinogen function and fibrin formation simultaneously enhancing TG on the poorly polymerizing fibrin strands, when fibrin's antithrombin I -like function is absent. Our study suggests an inverse link between low FXIII levels and enhanced TG modifying structure-function relationship of fibrin to support hemostasis.
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Authors
Hanna H. Pitkänen, Annukka Jouppila, Marja Lemponen, Minna Ilmakunnas, Jouni Ahonen, Riitta Lassila,