Only minor changes in thrombin generation of children and adolescents with type 1 diabetes mellitus

Article ID	Journal	Published Year	Pages	File Type
5622207	Thrombosis Research	2016	5 Pages	PDF

Abstract

Taken together, we found only minor changes of thrombin generation in children and adolescents with type 1 diabetes which - in contrast to type 2 diabetes - do not argue for a hypercoagulable state.

Keywords

ttpeak CAT APTT tPA factor VIII coagulant activity PPP FII vWF TFPI ETP FVIII:C PAI-1 NIDDM IDDM F1 + 2 antithrombin TAT Calibrated automated thrombography Thrombin generation Insulin-dependent diabetes mellitus non-insulin-dependent diabetes mellitus time to peak activated partial thromboplastin time prothrombin time Tissue factor Von Willebrand factor tissue plasminogen activator thrombin-antithrombin complex Tissue factor pathway inhibitor Plasminogen activator inhibitor type 1 endogenous thrombin potential prothrombin platelet-poor plasma

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Only minor changes in thrombin generation of children and adolescents with type 1 diabetes mellitus - A case-control study

Authors

Christina Cimenti, Axel Schlagenhauf, Bettina Leschnik, Elke Fröhlich-Reiterer, Hildegard Jasser-Nitsche, Harald Haidl, Elisabeth Suppan, Gudrun Weinhandl, Maximilian Leberl, Martin Borkenstein, Wolfgang E. Muntean,