Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5623052 | Alzheimer's & Dementia | 2013 | 7 Pages |
Abstract
Low Aβ42 was the strongest predictor of clinical progression in patients with subjective complaints. These results are in line with the hypothesis that the cascade of pathologic events starts with deposition of Aβ42, whereas neuronal degeneration and hyperphosphorylation of tau are more downstream events, closer to clinical manifestation of AD.
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Authors
Argonde C. van Harten, Pieter Jelle Visser, Yolande A.L. Pijnenburg, Charlotte E. Teunissen, Marinus A. Blankenstein, Philip Scheltens, Wiesje M. van der Flier,