Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5623698 | Alzheimer's & Dementia | 2017 | 11 Pages |
Abstract
Our longitudinal data confirm a biphasic trajectory of changes in brain structure in preclinical AD. These have implications in AD trials, both in patient selection and the use of MRI as a surrogate marker of efficacy.
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Authors
Jordi Pegueroles, Eduard Vilaplana, Victor Montal, Frederic Sampedro, Daniel Alcolea, Maria Carmona-Iragui, Jordi Clarimon, Rafael Blesa, Alberto Lleó, Juan Fortea, Alzheimer's Disease Neuroimaging Initiative Alzheimer's Disease Neuroimaging Initiative,