Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5624327 | Alzheimer's & Dementia | 2013 | 5 Pages |
Abstract
The Alzheimer's disease (AD) Cognitive Behavior Section (ADAS-Cog) is the most commonly used cognitive test in clinical trials of AD. Recent trials have focused on people earlier in the course of disease; however, there are concerns about using the ADAS-Cog at this crucial stage. Using data from the Alzheimer's disease Neuroimaging Initiative study, we used a range of traditional psychometric tests to evaluate those concerns. This issue of Alzheimer's & Dementia includes two articles that evaluate the ADAS-Cog. These articles report evaluations using two psychometric approaches: traditional methods and new methods. In this review, we provide accompanying background information to this program of research.
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Authors
Holly B. Posner, Stefan Cano, Maria C. Carrillo, Ola Selnes, Yaakov Stern, Ronald G. Thomas, John Zajicek, Jeremy Hobart, Alzheimer's Disease Neuroimaging Initiative Alzheimer's Disease Neuroimaging Initiative,