Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5627664 | Clinical Neurophysiology | 2017 | 10 Pages |
â¢Our novel method can show the spatiotemporal spread pattern of epileptic activity.â¢The reproducibility of its propagation pattern can be statistically confirmed.â¢The pattern was compared with that of FDG-PET hypometabolism in clinical cases.
ObjectiveWe describe temporal spread imaging (TSI) that can identify the spatiotemporal pattern of epileptic activity using Magnetoencephalography (MEG).MethodsA three-dimensional grid of voxels covering the brain is created. The array-gain minimum-variance spatial filter is applied to an interictal spike to estimate the magnitude of the source and the time (Ta) when the magnitude exceeds a predefined threshold at each voxel. This calculation is performed through all spikes. Each voxel has the mean Ta (