Case Report & Case SeriesVagus nerve stimulation therapy improved refractory epilepsy secondary to acute encephalitis with refractory, repetitive partial seizures (AERRPS)

•VNS was effective in a patient with AERRPS.•AERRPS may be a form of refractory post-encephalitic epilepsy (PEE).•VNS therapy may work in many patients with this type of PEE.

Acute encephalitis with refractory, repetitive partial seizures (AERRPS) is a rare condition. The seizure control of this encephalopathy is poor. The purpose of this report is to evaluate the utility of vagus nerve stimulation (VNS) in a patient with AERRPS. A 14-year-old boy presented with fever and headache. He developed epileptic facial twitching and eyelid fluttering. Various types of antiepileptic drugs did not control his seizures. He underwent VNS at the age of 21.After 5 years of VNS therapy, his seizure frequency decreased from daily to monthly.For patients with AERRPS, VNS may be a treatment option.