Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5630559 | Neurobiology of Disease | 2017 | 27 Pages |
Abstract
This study has therefore shown for the first time that local expression of mHTT in the dentate gyrus has deleterious effects, including its neurogenic capacity, with functional behavioural consequences, which fits well with recent data on hippocampal deficits seen in patients with HD.
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Authors
LC Schwab, K Richetin, RA Barker, N Déglon,