| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5630724 | Neurobiology of Disease | 2017 | 12 Pages |
Abstract
Chronic pain affects more than 20% of the UK population. Neurotrophic factors have been identified as therapeutic targets to improve current treatments of chronic pain. This review article focuses on nerve growth factor (NGF) and interleukin-6 (IL-6) as potential therapeutic targets. In this review we highlight the mechanisms of action and the current progress of targeted therapies in clinical trials.
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Authors
Jayne H. Kelleher, Damini Tewari, Stephen B. McMahon,