L'aphasie progressive primaire (APP) sous toutes ses formes

Primary progressive aphasia is a syndrome that has three clinical forms: non-fluent/agrammatism aphasia, semantic aphasia, and logopenic aphasia. The corresponding neuropathological lesions are frontotemporal degeneration or Alzheimer's disease. Each form of primary progressive aphasia corresponds to a specific linguistic description. Clinicopathological correlations are uncertain. Biomarkers may help the clinician to identify neuropathological hallmarks. In memory clinics, it is important to propose investigations useful for the identification of language impairment. We report the salient signs of each form to help the diagnosis and care.