Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5634590 | World Neurosurgery | 2017 | 25 Pages |
Abstract
Our retrospective analysis suggested that the presence of an IDH1 (R132H) mutation, frontal tumor location, and WHO grade of the initial tumor are associated with OS after progression to sGBM. In addition, some patients with sGBM may benefit from complete tumor resection depending on these patient-specific parameters. This is a finding that will ultimately need prospective validation.
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Authors
Florian Gessler, Johannes Zappi, Juergen Konczalla, Joshua D. Bernstock, Marie-Therese Forster, Marlies Wagner, Michel Mittelbronn, Volker Seifert, Christian Senft,