Interleukin 6 in the Cerebrospinal Fluid as a Biomarker for Onset of Vasospasm and Ventriculitis After Severe Subarachnoid Hemorrhage

Article ID	Journal	Published Year	Pages	File Type
5634812	World Neurosurgery	2017	21 Pages	PDF

Abstract

CSFIL-6 is increased after aSAH in patients with cVSSAH or VCSAH. Patients with a CSFIL-6 level higher than a C-OFF of 3100 pg/mL have an increased likelihood for VCSAH; patients with CSFIL-6 levels between 530 and 3100 pg/mL have an increased posttest probability for cVSSAH.

Keywords

TCD SAH MRA EVD aSAH GOS CTA DSA WFNS IL-6 ILR AUC Aneurysm Computed tomography angiography Magnetic resonance angiography interleukin 6 ICU intensive care unit external ventricular drain computed tomography Subarachnoid hemorrhage Aneurysmal subarachnoid hemorrhage TCD, Transcranial Doppler World Federation of Neurosurgical Societies CSF Cerebrospinal fluid Glasgow Outcome Scale area under the curve positive likelihood ratio negative likelihood ratio Cerebral vasospasm C-reactive protein CRP