Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn

Article ID	Journal	Published Year	Pages	File Type
5636157	Burns	2017	13 Pages	PDF

Abstract

In conclusion, CSE deficiency improves organ function and attenuates the inflammatory response in a murine model of burn.

Keywords

7-azido-4-methylcoumarin PAG TST ALT CBS AOAA CSE H2S 3-MST AzMC MDA PBS TNF 3-mercaptopyruvate sulfurtransferase MPO Alanine aminotransferase ALP Alkaline phosphatase Angiogenesis aminooxyacetic acid inflammation interferon IFN interleukin ANOVA one-way analysis of variance Oxidative stress BUN rhodanese Burns Hydrogen sulfide Cysteine cystathionine-beta-synthase tumor necrosis factor Phosphate buffered saline myeloperoxidase blood urea nitrogen Propargylglycine

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Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn

Authors

Akbar Ahmad, Nadiya Druzhyna, Csaba Szabo,