Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5637941 | Archives of Oral Biology | 2017 | 6 Pages |
Abstract
While IL-10 producing CD19+ B cells are present in the gingival tissues of patients with periodontal disease and of those with a healthy periodontium, the diseased gingival tissues had a much greater number of these cells than the healthy. The mRNA and protein levels of IL-10, IL-1β, and RANKL, as well as mRNA levels of TNF-α, were positively correlated with the number of IL-10 producing CD19+ B cells, which highlights the importance of these factors in the development and progression of periodontitis.
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Authors
Jiayin Dai, Liangjia Bi, Jiang Lin, Feng Qi,