Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
56386 | Catalysis Today | 2011 | 4 Pages |
Abstract
New homogeneous catalyst comprised of [Ru(methallyl)2(cod)] (cod = 1,5-cyclooctadiene) (1) and 2-diphenylphosphanyl-4-pyridyl(dimethyl)amine (2) is shown to efficiently catalyze the hydration of various nitriles under neutral conditions. The hydration proceeds in the presence of 0.5 mol% of the ruthenium catalyst at 80 °C in 1,2-dimethoxyethane solution and the corresponding amide is obtained within few hours without the formation of byproducts. Comparison of some phosphine ligands for the hydration reveals that the dimethylamino moiety of 2 improves the catalytic performance dramatically.
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Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Makoto Muranaka, Isao Hyodo, Wataru Okumura, Toshiyuki Oshiki,