Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5640107 | Journal of Cranio-Maxillofacial Surgery | 2017 | 12 Pages |
Abstract
This is the first large animal model to show a 100% incidence of MRONJ at all extraction sites in bisphosphonate pretreated animals (group 2). In addition, in this preclinical model for MRONJ it is shown that tooth extractions are not mandatory for a MRONJ manifestation. MRONJ also developed in areas of gingival or periodontal infections.
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Authors
Sven Otto, Christoph Pautke, Olga Martin Jurado, Dirk Nehrbass, Martin J. Stoddart, Michael Ehrenfeld, Stephan Zeiter,