| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5640162 | Journal of Cranio-Maxillofacial Surgery | 2017 | 36 Pages |
Abstract
A bisphosphonate-derived shift of macrophage polarization towards M1-polarized macrophages might impair bone tissue homeostasis and thus contribute to the pathogenesis of BRONJ. The observed increase in osteoclast density might be caused by BP-induced prolonged osteoclast survival.
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Authors
Falk Wehrhan, Patrick Moebius, Kerstin Amann, Jutta Ries, Raimund Preidl, Friedrich W. Neukam, Manuel Weber,