Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5641100 | Journal of Endodontics | 2017 | 8 Pages |
Abstract
The repair of periapical tissues with REPs of open apex teeth with apical periodontitis and in nonsurgical endodontic retreatment appears to be feasible in adults, but no regeneration was obtained in any of the present cases. The use of PRP may be a good choice as an autologous matrix because of its stability and induction; it contains growth factors and bioactive molecules like transforming growth factor beta, bone morphogenic proteins, insulinlike growth factors, and angiogenetic growth factors, which stimulate collagen production, angiogenesis, and cell differentiation. Anti-inflammatory and antibacterial properties have also been reported for this preparation, which are involved in all processes of repair.
Keywords
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Authors
José Francisco DDS, Javier DDS, MSc, MarÃa C. PhD, MD, DDS, Esther PhD, MD, DDS, BenjamÃn PhD, MD, DDS, Juan José PhD, MD, DDS, José PhD, MD, DDS,