| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5641747 | Journal of Oral and Maxillofacial Surgery | 2017 | 31 Pages |
Abstract
Three days of postoperative cefazolin and cephalexin markedly decreases SSI rates compared with 1Â day. However, the number needed to treat of 10 suggests that the benefits of the extended regimen might not outweigh the risks. The high prevalence of SSIs at the mandibular BSSO incisions might have been caused by contamination, with more saliva and reception of a lower blood supply, than maxillary Le Fort I incisions. Mandibular osteotomies could benefit from an extended antibiotic regimen to minimize SSIs and associated complications. Other surgical variables might not require special consideration for antibiotic therapy.
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Authors
Clayton M. DDS, MD, MSc, Curtis E. DDS, MD, MSc, Ian MD, Thomas W. BSc,