Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5644221 | Actas Dermo-Sifiliográficas | 2017 | 6 Pages |
Abstract
Photodynamic therapy (PDT) has been shown to be useful and effective in the treatment of actinic keratosis, Bowen disease, and basal cell carcinoma. We present a series of 13 Bowen disease lesions treated using PDT. Complete responses were achieved in 11 (84%) of the lesions after 3 months of treatment; at 18 months, complete responses were seen in 9 (70%) of the lesions. Patients who presented a partial response or recurrence were treated with topical 5% imiquimod and achieved complete responses. The lesions that presented partial response or recurrence were the largest lesions, between 3 and 5Â cm in diameter. PDT in monotherapy or combined sequentially with imiquimod is an excellent and well-tolerated therapeutic option for Bowen disease. The treatment has few adverse effects and shows satisfactory results, particularly in multiple large lesions in areas of difficult surgical reconstruction or in elderly patients with a high surgical risk.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
A.M. Victoria-MartÃnez, L. MartÃnez-Leborans, J.M. Ortiz-Salvador, A. Pérez-Ferriols,