Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5646409 | Journal of Allergy and Clinical Immunology | 2016 | 56 Pages |
Abstract
AHR is common in patients with mild-to-moderate COPD, affecting 1 in 4 patients and identifies a distinct subset of patients who have increased risk of disease progression and mortality. AHR may represent a spectrum of the asthma-COPD overlap phenotype that urgently requires disease modification.
Keywords
AHRAsthma-COPD overlap syndromeACoSBDRICSAICFDRLHSadiponectinAirway obstructionAirway hyperreactivityCOPDChronic obstructive pulmonary diseaseLung function testsrespiratory hypersensitivitybody mass indexBMILung Health StudyAkaike information criterionfalse-discovery rateDeath ratebronchodilator responseInhaled corticosteroid
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Authors
Ruzena MD, PhD, Darlene L.Y. MSc, Judith M. PhD, Janice M. MD, Pieter S. PhD, Maarten MD, PhD, Lisette MD, Zsuzsanna PhD, Donald MD, Robert MD, John PhD, Raymond PhD, Bruce MD, PhD, S.F. MD, Dirkje S. MD, PhD, Don D. MD,