Pyruvate dehydrogenase has a major role in mast cell function, and its activity is regulated by mitochondrial microphthalmia transcription factor

Article ID	Journal	Published Year	Pages	File Type
5646475	Journal of Allergy and Clinical Immunology	2017	53 Pages	PDF

Keywords

RBL OVA OXPHOS FADH2 Hsp PLA PDC DNP PGC-1α MITF PDH AHR BMMC CBMC DMSO Small interfering RNA ROS siRNA Proximity ligation assay Asthma Allergy Ovalbumin BALF empty vector Dinitrophenyl Dimethyl sulfoxide Bone marrow–derived mast cell Cytokines Microphthalmia transcription factor Microphthalmia-associated transcription factor Oxidative phosphorylation Degranulation Rat basophil leukemia Mast cells Bronchoalveolar lavage fluid Mitochondria NADH Airway hyperresponsiveness Heat shock protein pyruvate dehydrogenase pyruvate dehydrogenase complex Reactive oxygen species

Related Topics

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Pyruvate dehydrogenase has a major role in mast cell function, and its activity is regulated by mitochondrial microphthalmia transcription factor

Authors

Israa MSc, Tal PhD, Nadine PhD, Miri PhD, Alex MSc, Inbal PhD, Gillian PhD, Ziv PhD, Sagi MD, PhD, Neville MD, PhD, Francesca PharmD, PhD, Ehud PhD,