| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5646477 | Journal of Allergy and Clinical Immunology | 2017 | 9 Pages |
Abstract
Germline heterozygous IKZF1 mutations cause dysgammaglobulinemia; hematologic abnormalities, including B-cell defect; and autoimmune diseases.
Keywords
HSCTLMPPB-Cell precursor acute lymphoblastic leukemiaIKZF1BCP-ALLWESHSCCMPCLPGMPPh+electrophoresis mobility shift assayIkarosDNA bindingZinc fingerAutoimmune diseaseWhole-exome sequencingGermline mutationHematopoietic stem cellEMSA یا electrophoretic mobility shift assay Acute lymphoblastic leukemiaSystemic lupus erythematosusSLENuclear localizationwild-typeITPImmune thrombocytopenic purpuracommon lymphoid progenitorHematopoietic stem cell transplantationcommon myeloid progenitor
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Authors
Akihiro MD, PhD, Satoshi MD, PhD, Kenichi MD, PhD, Naonori MD, PhD, Yusuke MD, PhD, Hiroo MD, Motoi MD, Tsubasa MD, Miyuki PhD, Shiho MD, Sonoko MD, Masao MD, PhD, Haruna MD, Junji MD, PhD, Kanako MD, Takuya MD, Shouichi MD, PhD, Yozo MD, PhD,