| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5646608 | Journal of Allergy and Clinical Immunology | 2017 | 72 Pages |
Abstract
Therefore our findings identify PKC-θ as a critical factor for ILC2 activation that contributes to TH2 cell differentiation, which is associated with IRF4 and NFAT1 expression in allergic lung inflammation.
Keywords
FACSNFAT1Type 3 innate lymphoid cellILC1C20ILC3IRF4BMDCHDMILC2TregPKCILCBALFOXP3OVATCrEPOnatural killerAllergic asthmaeosinophil peroxidaseEosinophilsperiodic acid–SchiffOvalbuminBALFforkhead box P3fluorescence-activated cell sortingDendritic cellinnate lymphoid cellBone marrow–derived dendritic cellInnate lymphoid cellsInterferon regulatory factor 4Nuclear Factor of Activated T Cellsphycoerythrinbronchoalveolar lavageBronchoalveolar lavage fluidRegulatory T PAStype 2 innate lymphoid cellwild-typeProtein kinase CHouse dust miteT-cell receptor
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Fahima PhD, Pauline MSc, Chloé MSc, Louis MSc, Tiffany PhD, Nathalie BSc, Aurélie BSc, Margaux BSc, Vincent PhD, Laurent PhD, Quentin MSc, Lionel PhD, François PhD, Marc PhD, Fabrice PhD, Valérie F.J. PhD, Bernhard MD, PhD, Dieudonnée PhD,