| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5646671 | Journal of Allergy and Clinical Immunology | 2016 | 7 Pages |
Abstract
On the basis of our experience, we would suggest that PBSCs should be the stem cell source of choice in children with PIDs undergoing transplantation with Flu/Melph RIC from a matched donor source. This is most likely to ensure sustained high-level donor chimerism.
Keywords
RICPrimary immunodeficiency disorderGvHDmismatched unrelated donorDLIPBSCcGVHDaGVHDMFDHSCTPIDMSDMMFSCIDMatched unrelated donorMatched sibling donorAcute graft-versus-host diseaseGraft-versus-host diseaseChronic graft-versus-host diseaseDonor lymphocyte infusionReduced-intensity conditioningPeripheral blood stem cellChimerismmycophenolate mofetilbone marrowSCID, Severe combined immunodeficiencyHematopoietic stem cell transplantationReduced intensityMixed chimerismMud
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Authors
Kanchan MRCPCH, MNAMS, Stuart PhD, Waseem MD, PhD, Zoe BSc, MPH, Austen MRCP, MD, PhD, Juliana MD, Giovanna MD, Robert MD, Paul FRCP, FRCPath, Persis PhD, FRCP, FRCPath,