| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5646777 | Journal of Allergy and Clinical Immunology | 2016 | 6 Pages |
Abstract
By integrating genetic and epigenetic data, we identified that a differentially methylated CpG site within the melatonin receptor 1A (MTNR1A) gene mediates the effect of a paternally transmitted genetic variant on the comorbidity of asthma and AR. This study provides a novel insight into the role of epigenetic mechanisms in patients with allergic respiratory diseases.
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Authors
Chloé PhD, Catherine PhD, Giovanni PhD, Miriam F. DPhil, Marie-Hélène PhD, Andréanne MSc, Quentin B. MD, PhD, Klaus PhD, Jorge PhD, Patricia PhD, Liming PhD, Young-Ae MD, Jean MD, Valérie PhD, Pier Franco MD, William O. MD, DPhil, Mark PhD, Tomi MD,