| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5646782 | Journal of Allergy and Clinical Immunology | 2016 | 14 Pages |
Abstract
PAI-1 expression is significantly increased in the epithelium in patients with EoE and reflects fibrosis, and its inhibition decreases TGF-β1-induced gene expression. Epithelial PAI-1 might serve as a marker of EoE severity and form part of a TGF-β1-induced profibrotic network.
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Authors
Renee BS, Tom BS, Robert O. MD, Melissa BA, Ashmi MD, Braxton Bell, David H. MB, ChB, Ranjan MD, Richard PhD, Seema S. MD, PhD,