| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5646786 | Journal of Allergy and Clinical Immunology | 2016 | 14 Pages |
Abstract
IgG4-RD is prominently linked to clonally expanded IL-1β- and TGF-β1-secreting CD4+ CTLs in both peripheral blood and inflammatory tissue lesions. These active, terminally differentiated, cytokine-secreting effector CD4+ T cells are now linked to a human disease characterized by chronic inflammation and fibrosis.
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Authors
Hamid PhD, Vinay S. MBBS, PhD, Takashi DDS, PhD, Vikram MD, Emanuel MD, Zachary S. MD, Maria BS, Jefte M. MD, Joe BS, Mollie N. MD, Flavia V. MD, James R. MD, PhD, John H. MD, MPH, Shiv MBBS, PhD,