Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5647192 | Journal of Allergy and Clinical Immunology | 2017 | 44 Pages |
Abstract
Our results provide a new model for the CD23-IgE interaction. We show that the stalk region of CD23 is crucially involved in IgE binding and that the interaction can be blocked by the therapeutic anti-IgE antibody omalizumab.
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Immunology
Authors
Regina PhD, Julia MD, PhD, Teresa E. PhD, Christian MD, Andrea MSc, Gerhard MSc, Margarete PhD, Barbara PhD, Birgit PhD, Heimo PhD, Adolf MD, Walter PhD, Kenneth H. PhD, Rudolf MD, Verena MD,