Article ID Journal Published Year Pages File Type
5648892 Journal of Dermatological Science 2017 28 Pages PDF
Abstract
We show that Scurfy mice show a predominant AC-5 ANA pattern typical for mixed connective tissue disease as in scleroderma. The autoimmune inflammation in scurfy skin mainly consists of CD4+ T cells with Th2 differentiation and alternatively-activated (M2) macrophages as it is found in scleroderma with advanced fibrosis.
Related Topics
Health Sciences Medicine and Dentistry Dermatology
Authors
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