| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5649503 | Journal of Investigative Dermatology | 2017 | 7 Pages |
Abstract
Progress in genome sequencing achieved during the last two decades revealed that only about 2% of the genome codes for proteins, while the largest genome fraction is encoding thousands of non-coding RNAs. Non-coding RNAs play indispensable roles in regulating the activity and stability of the genome. Recent research in the area of the non-coding transcriptome signified the crucial roles for RNA regulatory networks in the normal development and their implications in a variety of pathological conditions. Here, recent advances in our understanding of non-coding RNA-mediated regulation of skin development and homeostasis are highlighted, focusing mainly on the regulatory roles of miRNAs and lncRNAs.
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Authors
Natalia V. Botchkareva,