Article ID Journal Published Year Pages File Type
5649903 Journal of Investigative Dermatology Symposium Proceedings 2017 4 Pages PDF
Abstract
Keloids are an exuberant response to cutaneous wound healing. Several lines of evidence suggest that keloid scarring is influenced by genetic factors. This review will discuss our current understanding of genetic influences on keloidal scarring via familial inheritance patterns; ethnic differences in prevalence; syndromes with keloid occurrence; linkage analysis, genome-wide association studies, and admixture mapping studies; transforming growth factor beta and p53 variant studies; and human leukocyte antigen polymorphisms.
Related Topics
Health Sciences Medicine and Dentistry Dermatology
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