Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5654804 | Clinical Immunology | 2017 | 35 Pages |
Abstract
In SVR patients, myeloid DC frequency transiently decreased, and returned to baseline level when telaprevir was stopped. Moreover, an up-regulation of CD80 and CD86 on mDC was observed in SVR patients as well as an improvement of IFN-α production by plasmacytoid DC, able to inhibit in vitro HCV replication.
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Authors
Alessandra Sacchi, Nicola Tumino, Federica Turchi, Giulia Refolo, GianMaria Fimia, Fabiola Ciccosanti, Marzia Montalbano, Raffaella Lionetti, Chiara Taibi, Gianpiero D'Offizi, Rita Casetti, Veronica Bordoni, Eleonora Cimini, Federico Martini,