| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5655038 | Diabetes & Metabolism | 2017 | 8 Pages |
Abstract
Adipose tissue of awake OSAS subjects appears no more hypoxic than adipose tissue of BMI-matched controls despite daytime hypoxaemia. Increased adipose tissue blood flow may be explained by an increased inflammatory response. We observe features of adipose dysfunction in subjects with OSAS, which attribute to increased cardiometabolic risk associated with this condition.
Keywords
LPLSao2HbO2CPAPOSASDSILEPCdh5aHIADIPOQTGFB1HOMA-IRVEGFAPECAMTNFaPPARGOxyhaemoglobinIL-6HIF1aadiponectinfatty acid synthaseArterial oxygen saturationinterleukin-6Adipose tissueTransforming growth factor β1tumour necrosis factor αobstructive sleep apnea syndromeApnea hypopnea indexoxygen desaturation indexhypoxia inducible factor 1 alphaVascular endothelial growth factor AFasnContinuous positive airway pressureLeptinLipoprotein lipaseObesityHypoxiamonocyte chemoattractant protein-1Collagencol
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Authors
C.E. Thorn, B. Knight, E. Pastel, L.J. McCulloch, B. Patel, A.C. Shore, K. Kos,