Using continuous glucose monitoring to assess contributions of premeal and postmeal glucose levels in diabetic patients treated with metformin alone

In patients treated with metformin alone, BEG was the major contributor to excess glycaemia at HbA1c levels ≥ 7.7%, while PEG and BEG contributions were similar and stable below this level. For HbA1c levels ≥ 7.7%, add-on therapy to metformin should preferentially target control of BEG, whereas targeting both BEG and PEG could be of equivalent importance with lower HbA1c levels.