Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5656919 | Nutrition | 2017 | 7 Pages |
Abstract
- Ghrelin is an acylated peptide hormone stimulating food intake and adiposity;
- Previous data showed that (i) ghrelin is protected from degradation by plasma immunoglobulin (Ig) G; (ii) plasma IgG from obese humans and mice enhanced ghrelin's orexigenic effect; and (iii) obese humans and mice display increased affinity of plasma IgG for ghrelin.
- Here we show that affinity of plasma IgG for ghrelin is increased in obese Zucker rats.
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Authors
Nicolas Ph.D., Romain Ph.D., Jonathan Ph.D., Pierre M.D., Ph.D., Sergueï O. M.D., Ph.D.,