| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5657193 | Clinical Gastroenterology and Hepatology | 2017 | 33 Pages |
Abstract
In a systematic review and meta-analysis, we found that urine levels of IL18 and NGAL from patients with cirrhosis discriminate between those with ATN and other types of kidney impairments, with AUC values of 0.88 and 0.89, respectively. Urine levels of IL18 and NGAL identified patients with short-term mortality with an AUC value of 0.76. These biomarkers might be used to determine prognosis and select treatments for patients with cirrhosis.
Keywords
prerenal azotemiaNGALPRAAKIHRSATNAUCacute kidney injuryinterleukinFeNaSurvivalfractional excretion of sodiumhepatorenal syndromeCytokinePrognostic factorconfidence intervalneutrophil gelatinase-associated lipocalinarea under the receiver-operating characteristic curveAcute tubular necrosisPrediction
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Authors
Jeremy Puthumana, Xavier Ariza, Justin M. Belcher, Isabel Graupera, Pere Ginès, Chirag R. Parikh,