| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5657288 | Clinical Gastroenterology and Hepatology | 2017 | 36 Pages |
Abstract
In a prospective study of 3466 individuals who underwent screening colonoscopies and received FITs, we found that use of fresh vs frozen samples slightly affected positivity rates and the proportions of CRCs or adenomas detected at the recommended Hgb cutoff value. However, after we adjusted Hgb cutoff values to produce equal proportions of positive results for fresh vs frozen samples, the performance of the FIT was similar with each sample type. Season of sample collection (based on outdoor temperature) did not affect detection of CRC using either sample type in this study from Middle Europe.
Keywords
gFOBTIQRPPVROCAUCLR+fecal immunochemical testguaiac-based fecal occult blood testpositive predictive valuenegative predictive valueVariationColorectal cancerColon cancerconfidence intervalEnvironmental factorsinterquartile rangeNPV یا negative predictive valueFITarea under the curvepositive likelihood rationegative likelihood ratioSamplingHemoglobinHgbCRCreceiver operating characteristic
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Authors
Hongda Chen, Simone Werner, Hermann Brenner,